This week on Supernatural the Winchester brothers Sam (Jared Padalecki) and Dean (Jensen Ackles) have split up, with Sam on a journey of self-discovery and Dean on a mission to.... deflower an Angel?  Seriously!

As Dean and Castiel (Misha Collins) wait to perform a ritual that will likely result in the Angel's death, the wiliest of the Winchester's decides he can't let his Angel buddy die a virgin.  This is going to be one interesting episode.

On the Sam side of things, look for the youngest of the brothers to be the first to encounter Lucifer.  We are also going to be treated to the lovely visage of Adrianne Palicki, who played Sam's fiance in season one.  That's right, this season of Supernatural is all about the nostalgia!

ADRIANNE PALICIKI GUEST STARS — Not sure he trusts himself anymore, Sam (Jared Padalecki) decides to give up hunting, but a late-night visitor (guest star Adrianne Palicki) won’t let him off the hook that easily.  Dean (Jensen Ackles), intent on stopping the Apocalypse, continues hunting on his own and teams up with Castiel (Misha Collins) to find the Archangel Raphael, as Castiel believes Raphael knows God’s location.  Miller Tobin directed the episode written by Jeremy Carver (#503).